Guatemala 2018: Facing A Constitutional Crossroad

Mathematical Proofs at a Crossroad?

For more than 2000 years, from Pythagoras and Euclid to Hilbert and Bourbaki, mathematical proofs were essentially based on axiomatic-deductive reasoning. In the last decades, the increasing length and complexity of many mathematical proofs led to the expansion of some empirical, experimental, psychological and social aspects, yesterday only marginal, but now changing radically the very essence...

Constitutional Theory, Constitutional Culture

Constitutional theorists and other constitutional commentators make heavy use of a paradigm that mistakes certain aspects of our current constitutional decisionmaking process for inherent parts of our constitutional structure and ignores other important aspects of that process entirely. These distortions and elisions raise concerns about the accuracy of much descriptive constitutional commentar...

Constitutional Economics/Constitutional Politics

Why does the treatment of American constitutional politics presented in We the People depart so radically from models of constitutional deliberation developed in the type of constitutional economics pioneered by James Buchanan and Gordon Tullock? The paper defines three premises that account for the divergence, and concludes by proposing an inquiry into constitutional design that requires insig...

Arthritis clinical trials at a crossroad.

Intronic microRNAs: a crossroad in gene regulation.

Most human genes transcribed by RNA Pol II (polymerase II) contain short exons separated by long tracts of non-coding intronic sequences. In addition to their role in generating proteomic diversity through the process of alternative splicing, intronic sequences host many ncRNAs (non-coding RNAs), involved in various gene regulation processes. miRNAs (microRNAs) are short ncRNAs that mediate eit...